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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78297 |
Aldafermin
NGM282 |
||
Aldafermin (NGM282),一种成纤维细胞生长因子19的类似物,主要用于非酒精性脂肪性肝炎(NASH)的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02907 |
FGF-19 Protein, Human, Recombinant
fibroblast growth factor 19 |
Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca... | |||
TMPJ-00715 |
FGF-19 Protein, Human, Recombinant (His)
FGF-19,Fibroblast growth fact... |
Human | E. coli |
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ... | |||
TMPK-01150 |
Beta Klotho Protein, Mouse, Recombinant (His)
Klotho beta,β-klotho,MGC142213,βKlotho,β Klotho,KLB,beta-klo... |
Mouse | HEK293 Cells |
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the acce... | |||
TMPK-01078 |
Beta Klotho Protein, Human, Recombinant (His)
beta-klotho,MGC142213,betaKlotho,BKL,β-klotho,KLB,klotho bet... |
Human | HEK293 Cells |
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 111.6 kDa and the acces... |